{"id":492,"date":"2026-04-16T13:47:21","date_gmt":"2026-04-16T13:47:21","guid":{"rendered":"https:\/\/www.vailhealthbh.org\/optimize\/"},"modified":"2026-09-29T20:27:10","modified_gmt":"2026-09-29T20:27:10","slug":"optimizar","status":"publish","type":"page","link":"https:\/\/www.vailhealthbh.org\/es\/optimize\/","title":{"rendered":"OPTIMIZAR Estudio"},"content":{"rendered":"<section \tclass=\"content-with-list\"\n\tstyle=\"--padding: 4.8rem;\">\n\n\t<div class=\"content-with-list__container container\">\n\n\t\t\n\t\t<div class=\"content-with-list__row\">\n\n\t\t\t<!-- Description Column -->\n\t\t\t\t\t\t\t<div class=\"content-with-list__description col\">\n\t\t\t\t\t<h5>Una Investigaci\u00f3n de Estrategias para Comprender y Optimizar los Efectos de la Psilocibina en la Depresi\u00f3n (Estudio OPTIMIZE)<\/h5>\n<p><strong>Investigador principal:<\/strong> Charles Raison, MD<\/p>\n<p>Vail Health Behavioral Health est\u00e1 llevando a cabo este estudio de investigaci\u00f3n para explorar los posibles efectos de la psilocibina en personas con depresi\u00f3n, particularmente cuando se combina con la estimulaci\u00f3n transcut\u00e1nea investigacional del nervio vago auricular (taVNS). La taVNS utilizada en este estudio es un procedimiento no invasivo que se realiza en casa y aplica una estimulaci\u00f3n el\u00e9ctrica suave en la oreja.<\/p>\n<p>La psilocibina es una droga con efectos psicod\u00e9licos temporales que no est\u00e1 aprobada por la Administraci\u00f3n de Alimentos y Medicamentos de los Estados Unidos (FDA).<\/p>\n<p><em>Por favor, tenga en cuenta que este estudio es \u00fanicamente con fines de investigaci\u00f3n y no est\u00e1 destinado como tratamiento. A continuaci\u00f3n, se proporcionan detalles adicionales sobre el estudio.<\/em><\/p>\n\t\t\t\t<\/div>\n\t\t\t\n\t\t\t<!-- List Section Column -->\n\t\t\t\t\t\t\t<div class=\"content-with-list__list-section col\">\n\n\t\t\t\t\t\t\t\t\t\t\t<h3 class=\"content-with-list__list-header\">Enlaces r\u00e1pidos<\/h3>\n\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"content-with-list__list-grid\">\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"#study-description\"\n\t\t\t\t\t\t\t\t\t   target=\"_self\"\n\t\t\t\t\t\t\t\t\t   class=\"content-with-list__list-item has-link\">\n\t\t\t\t\t\t\t\t\t\t<span class=\"content-with-list__icon\">\n\t\t\t\t\t\t\t\t\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"24\" height=\"24\" viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\" class=\"lucide lucide-arrow-right-icon lucide-arrow-right\"><path d=\"M5 12h14\" \/><path d=\"m12 5 7 7-7 7\" \/><\/svg>\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"content-with-list__item-text\">\n\t\t\t\t\t\t\t\t\t\t\tDescripci\u00f3n del estudio\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"#participant-info\"\n\t\t\t\t\t\t\t\t\t   target=\"_self\"\n\t\t\t\t\t\t\t\t\t   class=\"content-with-list__list-item has-link\">\n\t\t\t\t\t\t\t\t\t\t<span class=\"content-with-list__icon\">\n\t\t\t\t\t\t\t\t\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"24\" height=\"24\" viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\" class=\"lucide lucide-arrow-right-icon lucide-arrow-right\"><path d=\"M5 12h14\" \/><path d=\"m12 5 7 7-7 7\" \/><\/svg>\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"content-with-list__item-text\">\n\t\t\t\t\t\t\t\t\t\t\tInformaci\u00f3n sobre el participante\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"#compensation\"\n\t\t\t\t\t\t\t\t\t   target=\"_self\"\n\t\t\t\t\t\t\t\t\t   class=\"content-with-list__list-item has-link\">\n\t\t\t\t\t\t\t\t\t\t<span class=\"content-with-list__icon\">\n\t\t\t\t\t\t\t\t\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"24\" height=\"24\" viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\" class=\"lucide lucide-arrow-right-icon lucide-arrow-right\"><path d=\"M5 12h14\" \/><path d=\"m12 5 7 7-7 7\" \/><\/svg>\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"content-with-list__item-text\">\n\t\t\t\t\t\t\t\t\t\t\tCompensaci\u00f3n financiera\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"content-with-list__list-item\">\n\t\t\t\t\t\t\t\t\t\t<span class=\"content-with-list__icon\">\n\t\t\t\t\t\t\t\t\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"24\" height=\"24\" viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\" class=\"lucide lucide-arrow-right-icon lucide-arrow-right\"><path d=\"M5 12h14\" \/><path d=\"m12 5 7 7-7 7\" \/><\/svg>\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"content-with-list__item-text\">\n\t\t\t\t\t\t\t\t\t\t\tPreguntas frecuentes\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<div class=\"content-with-list__list-item\">\n\t\t\t\t\t\t\t\t\t\t<span class=\"content-with-list__icon\">\n\t\t\t\t\t\t\t\t\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"24\" height=\"24\" viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\" class=\"lucide lucide-arrow-right-icon lucide-arrow-right\"><path d=\"M5 12h14\" \/><path d=\"m12 5 7 7-7 7\" \/><\/svg>\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"content-with-list__item-text\">\n\t\t\t\t\t\t\t\t\t\t\tLocalizaci\u00f3n del estudio\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<a href=\"#contact\"\n\t\t\t\t\t\t\t\t\t   target=\"_self\"\n\t\t\t\t\t\t\t\t\t   class=\"content-with-list__list-item has-link\">\n\t\t\t\t\t\t\t\t\t\t<span class=\"content-with-list__icon\">\n\t\t\t\t\t\t\t\t\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"24\" height=\"24\" viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\" class=\"lucide lucide-arrow-right-icon lucide-arrow-right\"><path d=\"M5 12h14\" \/><path d=\"m12 5 7 7-7 7\" \/><\/svg>\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"content-with-list__item-text\">\n\t\t\t\t\t\t\t\t\t\t\tCont\u00e1ctese con nuestro equipo\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\n\t\t\t\t<\/div>\n\t\t\t\n\t\t<\/div>\n\n\t<\/div>\n\n<\/section>\n\n\n\n<div class=\"wp-block-buttons is-content-justification-left is-layout-flex wp-container-core-buttons-is-layout-b192c3d7 wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-primary\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/redcap.vumc.org\/surveys\/?s=TH8YLRAFXNLY3Y83\">Consulte si se encuentra en condiciones de precalificaci\u00f3n<\/a><\/div>\n<\/div>\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 id=\"study-description\" class=\"wp-block-heading\">Descripci\u00f3n del estudio<\/h2>\n\n\n\n<figure class=\"wp-block-table wp-block-table__container\"><div class=\"wp-block-table__custom-wrapper\"><table class=\"has-fixed-layout\"><tbody><tr><td>Condici\u00f3n<\/td><td>Depresi\u00f3n<\/td><\/tr><tr><td>Situaci\u00f3n general<\/td><td>Reclutamiento<\/td><\/tr><\/tbody><\/table><\/div><\/figure>\n\n\n\n<h4 class=\"wp-block-heading\">Qu\u00e9 implica<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">La participaci\u00f3n dura hasta 17 semanas e incluye:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Visita de cribado (4 horas) <\/strong>Evaluar la elegibilidad mediante ex\u00e1menes f\u00edsicos, cuestionarios y muestras de sangre\/orina.<\/li>\n\n\n\n<li><strong>Dos Visitas Basales (3-3.75 horas cada una): <\/strong>Complete los cuestionarios. Se tomar\u00e1 una muestra de sangre adicional durante la segunda visita de referencia.<\/li>\n\n\n\n<li><strong>Dos sesiones de preparaci\u00f3n (2 horas cada una):<\/strong> Prep\u00e1rate para la sesi\u00f3n de dosificaci\u00f3n con facilitadores capacitados<\/li>\n\n\n\n<li><strong>Sesi\u00f3n de dosificaci\u00f3n (8-10 horas): <\/strong>Toma 25 mg de psilocibina bajo supervisi\u00f3n.<\/li>\n\n\n\n<li><strong>Despu\u00e9s de la Sesi\u00f3n de Dosis: <\/strong>Los participantes ser\u00e1n asignados aleatoriamente a uno de los siguientes grupos para el <strong>semana posterior a la dosificaci\u00f3n:<\/strong>\n<ol class=\"wp-block-list\">\n<li><strong>Activa taVNS en Casa<\/strong> -Usa un dispositivo taVNS en casa dos veces al d\u00eda durante siete d\u00edas<\/li>\n\n\n\n<li><strong>Sham taVNS en casa<\/strong> <strong>\u2013 Usar una versi\u00f3n simulada (placebo) del dispositivo taVNS en casa dos veces al d\u00eda durante siete d\u00edas. <\/strong>Se ve y se siente como el dispositivo real, pero no ofrece estimulaci\u00f3n activa.<\/li>\n\n\n\n<li><strong>No taVNS<\/strong> \u2013 No usar\u00e1s un dispositivo taVNS durante este per\u00edodo.<\/li>\n<\/ol>\n<\/li>\n<\/ul>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Tres Sesiones de Integraci\u00f3n (1 hora cada una):<\/strong> Comenta y reflexiona sobre tus experiencias con facilitadores capacitados.<\/li>\n\n\n\n<li><strong>Cinco Visitas de Seguimiento (1.25-3 horas cada una): <\/strong>Complete cuestionarios y discuta y reflexione sobre sus experiencias. Se recolectar\u00e1 una muestra de sangre final durante la \u00faltima visita.<\/li>\n<\/ul>\n\n\n\n<p class=\"wp-block-paragraph\">Adem\u00e1s, completar\u00e1s cuestionarios y diarios de voz en casa usando la aplicaci\u00f3n Fabla antes y despu\u00e9s de la dosificaci\u00f3n. Adicionalmente, usar\u00e1s un dispositivo Android dedicado con una aplicaci\u00f3n de Grabadora Activada Electr\u00f3nicamente (EAR) para registrar fragmentos de sonido de tus actividades diarias antes y despu\u00e9s de la sesi\u00f3n de dosificaci\u00f3n.<\/p>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-primary\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/clinicaltrials.gov\/study\/NCT06512194?term=OPTIMIZE&amp;intr=psilocybin&amp;rank=1\" target=\"_blank\" rel=\"noopener\">Obtenga m\u00e1s informaci\u00f3n en ClinicalTrials.gov<\/a><\/div>\n<\/div>\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 id=\"participant-info\" class=\"wp-block-heading\">Informaci\u00f3n sobre el participante<\/h2>\n\n\n\n<h4 class=\"wp-block-heading\">Qui\u00e9n puede participar<\/h4>\n\n\n\n<figure class=\"wp-block-table wp-block-table__container\"><div class=\"wp-block-table__custom-wrapper\"><table class=\"has-fixed-layout\"><thead><tr><th>Los participantes deben<\/th><\/tr><\/thead><tbody><tr><td>1. Tener entre 18 y 70 a\u00f1os.<\/td><\/tr><tr><td>2. Si padeces depresi\u00f3n.<\/td><\/tr><tr><td>3. Habla ingl\u00e9s (es capaz de proporcionar consentimiento informado y completar cuestionarios en ingl\u00e9s).<\/td><\/tr><tr><td>4. Estar dispuesto a cumplir con todos los procedimientos de estudio y a estar disponible durante todo el per\u00edodo de estudio.<\/td><\/tr><tr><td>5. Ser capaz de tragar c\u00e1psulas.<\/td><\/tr><tr><td>6. Tener una salud f\u00edsica adecuada.<\/td><\/tr><\/tbody><\/table><\/div><\/figure>\n\n\n\n<h4 id=\"compensation\" class=\"wp-block-heading\">Compensaci\u00f3n financiera<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Los participantes recibir\u00e1n una compensaci\u00f3n por su tiempo y su participaci\u00f3n. La compensaci\u00f3n total puede ascender hasta $1,025, dependiendo del n\u00famero de visitas al estudio y de evaluaciones realizadas.<\/p>\n\n\n\n<div class=\"wp-block-buttons is-content-justification-left is-layout-flex wp-container-core-buttons-is-layout-b192c3d7 wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-primary\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/redcap.vumc.org\/surveys\/?s=TH8YLRAFXNLY3Y83\">Consulte si se encuentra en condiciones de precalificaci\u00f3n<\/a><\/div>\n<\/div>\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h3 id=\"faq\" class=\"wp-block-heading\">Preguntas Frecuentes (PF)<\/h3>\n\n\n\n<section \tclass=\"accordion\"\n\tstyle=\"--padding: 6rem\">\n\t<div class=\"accordion__container container aligncenter\">\n\t\t<div class=\"accordion__row justify-content-center\">\n\t\t\t<div class=\"accordion__col col color-scheme-1\">\n\t\t\t\t<!-- Heading & intro content-->\n\t\t\t\t\n\t\t\t\t<!-- Items -->\n\t\t\t\t<div class=\"accordion__items\">\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"accordion__item text-align-left\">\n\t\t\t\t\t\t\t<h3 class=\"accordion__item-title\">\n\t\t\t\t\t\t\t\t<button class=\"accordion__item-trigger flex-row align-items-center justify-content-space-between text-align-left\" aria-expanded=\"false\" aria-controls=\"block_7a96faffed094a8fc14240a7cdc875d5_accordion-panel-1\" id=\"block_7a96faffed094a8fc14240a7cdc875d5_accordion-title-1\">\n\t\t\t\t\t\t\t\t\t<span>\u00bfMe ayudar\u00e1 ser voluntario en este estudio?<\/span>\n\t\t\t\t\t\t\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"24\" height=\"24\" viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\" class=\"plus\"><path d=\"M5 12h14\" \/><path class=\"plus_v\" d=\"M12 5v14\" \/><\/svg>\t\t\t\t\t\t\t\t<\/button>\n\t\t\t\t\t\t\t<\/h3>\n\n\t\t\t\t\t\t\t<div class=\"accordion__item-panel\" id=\"block_7a96faffed094a8fc14240a7cdc875d5_accordion-panel-1\" role=\"region\" aria-labelledby=\"block_7a96faffed094a8fc14240a7cdc875d5_accordion-title-1\">\n\t\t\t\t\t\t\t\t<div class=\"accordion__item-panel-content\">\n\t\t\t\t\t\t\t\t\t<p>Recibir psilocibina con apoyo psicol\u00f3gico en un ensayo cl\u00ednico puede mejorar su bienestar. Si usted est\u00e1 en el grupo que recibe el tratamiento de estudio (estimulaci\u00f3n taVNS) despu\u00e9s de la dosificaci\u00f3n de psilocibina, esto podr\u00eda funcionar mejor que recibir psilocibina sola, pero actualmente no se sabe, por eso estamos realizando el estudio. La psilocibina y\/o la estimulaci\u00f3n taVNS podr\u00edan no funcionar en absoluto o podr\u00edan tener efectos secundarios desagradables. Incluso si el estudio no lo beneficia directamente, su participaci\u00f3n podr\u00eda ayudar a otras personas en el futuro al avanzar en nuestra comprensi\u00f3n de c\u00f3mo la psilocibina, combinada con la estimulaci\u00f3n taVNS, puede mejorar el bienestar.<\/p>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t\t<div class=\"accordion__item text-align-left\">\n\t\t\t\t\t\t\t<h3 class=\"accordion__item-title\">\n\t\t\t\t\t\t\t\t<button class=\"accordion__item-trigger flex-row align-items-center justify-content-space-between text-align-left\" aria-expanded=\"false\" aria-controls=\"block_7a96faffed094a8fc14240a7cdc875d5_accordion-panel-2\" id=\"block_7a96faffed094a8fc14240a7cdc875d5_accordion-title-2\">\n\t\t\t\t\t\t\t\t\t<span>\u00bfC\u00f3mo participar?<\/span>\n\t\t\t\t\t\t\t\t\t<svg xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"24\" height=\"24\" viewbox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\" class=\"plus\"><path d=\"M5 12h14\" \/><path class=\"plus_v\" d=\"M12 5v14\" \/><\/svg>\t\t\t\t\t\t\t\t<\/button>\n\t\t\t\t\t\t\t<\/h3>\n\n\t\t\t\t\t\t\t<div class=\"accordion__item-panel\" id=\"block_7a96faffed094a8fc14240a7cdc875d5_accordion-panel-2\" role=\"region\" aria-labelledby=\"block_7a96faffed094a8fc14240a7cdc875d5_accordion-title-2\">\n\t\t\t\t\t\t\t\t<div class=\"accordion__item-panel-content\">\n\t\t\t\t\t\t\t\t\t<p><!-- wp:paragraph --><\/p>\n<p>Si est\u00e1 interesado en unirse a nuestro estudio de investigaci\u00f3n, por favor complete el formulario de preselecci\u00f3n haciendo clic en el bot\u00f3n \u201cVer si pre-califica\u201d a continuaci\u00f3n. Esto nos ayudar\u00e1 a determinar si cumple con los requisitos iniciales para la participaci\u00f3n.<\/p>\n<p>Si califica, un miembro de nuestro equipo de estudio se pondr\u00e1 en contacto con usted para una entrevista de seguimiento y una evaluaci\u00f3n adicional.<\/p>\n<!-- \/wp:paragraph -->\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<\/div> <!-- .accordion__items -->\n\t\t\t<\/div> <!-- .accordion__col.col -->\n\t\t<\/div> <!-- .accordion__row.row -->\n\t<\/div> <!-- .accordion__container.container -->\n<\/section> <!-- .accordion -->\n\n\n<div style=\"height:15px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 id=\"location\" class=\"wp-block-heading\">Localizaci\u00f3n del estudio<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Cl\u00ednica Wiegers \u2013 Edificio B<\/strong><br>439 Edwards Access Road<br>Ste. B204<br>Edwards, CO 81632<\/p>\n\n\n\n<div class=\"wp-block-buttons is-layout-flex wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button is-style-outline is-style-outline--1\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/maps.app.goo.gl\/vzS12DfR4WwQbGmWA\" target=\"_blank\" rel=\"noopener\">Obtener direcciones<\/a><\/div>\n<\/div>\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<h2 id=\"contact\" class=\"wp-block-heading\">\u00bfPreguntas?<\/h2>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-63326995 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<h4 class=\"wp-block-heading\">Cont\u00e1ctese con nuestro equipo<\/h4>\n\n\n\n<p class=\"wp-block-paragraph\">Para cualquier pregunta adicional, por favor contacte al equipo del estudio OPTIMIZE en <a href=\"mailto:BHIC@vailhealth.org\">BHIC@vailhealth.org<\/a> o <a href=\"tel:9708557374\">(970) 855-7374<\/a>.<\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\">\n<figure class=\"wp-block-image size-large is-style-rounded\"><img decoding=\"async\" width=\"1024\" height=\"683\" src=\"http:\/\/www.vailhealthbh.org\/wp-content\/uploads\/sites\/3\/2026\/09\/Optimize-Web-1500x1001-2026-1-1024x683.jpeg\" alt=\"\" class=\"wp-image-1926\" srcset=\"https:\/\/www.vailhealthbh.org\/wp-content\/uploads\/sites\/3\/2026\/09\/Optimize-Web-1500x1001-2026-1-1024x683.jpeg 1024w, https:\/\/www.vailhealthbh.org\/wp-content\/uploads\/sites\/3\/2026\/09\/Optimize-Web-1500x1001-2026-1-300x200.jpeg 300w, https:\/\/www.vailhealthbh.org\/wp-content\/uploads\/sites\/3\/2026\/09\/Optimize-Web-1500x1001-2026-1-768x513.jpeg 768w, https:\/\/www.vailhealthbh.org\/wp-content\/uploads\/sites\/3\/2026\/09\/Optimize-Web-1500x1001-2026-1-18x12.jpeg 18w, https:\/\/www.vailhealthbh.org\/wp-content\/uploads\/sites\/3\/2026\/09\/Optimize-Web-1500x1001-2026-1.jpeg 1500w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n<\/div>\n<\/div>\n\n\n\n<div style=\"height:30px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>","protected":false},"excerpt":{"rendered":"<p>Study Description Condition Depression Overall Status Recruiting What&#8217;s Involved Participation lasts up to 17 weeks and includes: You&#8217;ll also complete questionnaires and voice diaries at home using the Fabla app before and after dosing. 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